Why AI-based computational pathology detects more cancers

<p>Chances are you or someone you love has had a biopsy to check for cancer. Doctors got a tissue sample and they sent it into a pathology lab, and at some point you got a result back. If you were lucky, it was negative and there was no cancer. But have you ever wondered exactly what happens in between those steps? Until recently, it’s been a meticulous but imperfect manual process where a pathologist would put a thin slice of tissue under a high-powered microscope and examine the cells by eye, looking for patterns that indicate malignancy. But now the process is going digital—and growing more accurate.</p><p>Harry's guest this week is Leo Grady, CEO of, Paige AI, which makes an AI-driven test called Paige Prostate. Grady says that in a clinical study, pathologists who had help from the Paige system accurately diagnosed prostate cancer almost 97 percent of the time, up from 90 percent without the tool. That translates into a 70 percent reduction in false negatives—nice odds if your own health is on the line. This week on the show, Grady explains explain how the Paige test works, how the company trained its software to be more accurate than a human pathologist, how it won FDA approval for the test, and what it could all mean for the future of cancer diagnosis and treatment.</p><p><strong>Please rate and review The Harry Glorikian Show on Apple Podcasts! </strong>Here's how to do that from an iPhone, iPad, or iPod touch:</p><p><strong>1. </strong>Open the Podcasts app on your iPhone, iPad, or Mac. </p><p><strong>2. </strong>Navigate to The Harry Glorikian Show podcast. You can find it by searching for it or selecting it from your library. Just note that you'll have to go to the series page which shows all the episodes, not just the page for a single episode.</p><p><strong>3. </strong>Scroll down to find the subhead titled "Ratings & Reviews."</p><p><strong>4. </strong>Under one of the highlighted reviews, select "Write a Review."</p><p><strong>5. </strong>Next, select a star rating at the top — you have the option