When Apoptosis Becomes Impaired: Targeting BCL-2

Guest: Matthew S. Davids, MD, MMSc <br> Guest: Andrew Souers, PhD <br> <p>Apoptosis is a normal and highly regulated process that the body uses to dispose of aged or damaged cells. But what happens when this critical cellular process becomes impaired? Together, Drs. Andy Souers and Matt Davids answer that question and more, like how the protein BCL-2 regulates apoptosis and how venetoclax binds and inhibits BCL-2.</p>