Using DNA Methylation to predict biological & functional ages

<p><span data-contrast="auto">Join Dr. Gladden on this conversation with Ryan Smith about epigenetic age testing and DNA methylation. Ryan has a biochemistry degree from the University of Transylvania. He went to medical school and started clinical rotations before realizing he didn't want to be a doctor. That's when he pivoted to the world of pharmacy, focusing on peptide synthesis, and opened up Tailor Made Compounding. Ryan has been very successful in his endeavors, with Tailor Made Compounding becoming the 4</span><span data-contrast="auto">th</span> <span data-contrast= "auto">fastest growing healthcare company at the time, investing in several other functional medicine spaces and, eventually, starting TruDiagnostic. This</span> <span data-contrast="none">is a CLIA certified lab and health data company focused and committed to research with over 30 approved clinical research studies investigating the epigenetic methylation changes of a variety of longevity and health interventions. They have created one of the largest private epigenetic health databases in the world with over 13,000 patients tested and continue to lead the space in epigenetic methylation interpretation and diagnostic prediction. In this episode, him and Dr. Gladden discuss how epigenetic age testing and DNA methylation have evolved, the different kinds of clocks that exist now and what they measure, as well as the advances being made and envisioned in the disease prevention and age reversal spaces.</span> </p> <p> </p> <p><span data-contrast="auto">Show notes:</span> </p> <p><span data-contrast="auto">00:55 Dr. Gladden gives a description of this episode and an introduction of Ryan Smith.</span></p> <p><span data-contrast="auto">02:20 Dr. Gladden explains why he is excited for this show.</span></p> <p><span data-contrast="auto">03:15 Ryan introduces the audience to TruAge and tells us the big takeaway from this testing.</span></p> <p><span data-contrast="auto">04:50 What is epigenetic methylation? What are the two main epigenetic marks? Ryan