Using biotechnology to maximise drug discovery output

<div style="font-weight: 400;"> <p><span data-contrast="auto">High-throughput screens are a recognised hit-finding process but the use of an integrated discipline approach is key to maximising the output from such a screening methodology. In the first article, Ian Linney and Scott Maidment from Charles River describe the value of integration of medicinal chemistry in this method. </span><span data-ccp-props= "{"201341983":0,"335559739":160,"335559740":259}"> </span></p> </div> <div style="font-weight: 400;"> <p><span data-contrast="auto">Thanks to continued advances in genetic engineering, investigators often find they can obtain the most relevant mouse model for their research by commissioning the custom generation of a model that best meets their need—whether it’s modelling a disease state, validating a gene target of interest, or testing a drug candidate in vivo. Caroline Horizny from Taconic Biosciences discusses this in the second article.</span><span data-ccp-props= "{"201341983":0,"335559739":160,"335559740":259}"> </span></p> </div>