TWiV 995: Viral origin stories

<p>TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid.</p> <p>Click arrow to play<br /> Download <a title="" href= "http://traffic.libsyn.com/twiv/TWiV995.mp3">TWiV 995</a> (74 MB .mp3, 123 min)<br /> Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode">Links for this episode</h3> <p>•Register for <a href="http://asv.org/asv2023">ASV 2023</a><br /> •<a href="https://discord.gg/xA4JX7AeeU">MicrobeTV Discord Server</a><br /> • More evidence for <a title="" href= "https://zenodo.org/record/7754299#.ZBszeC-B2oq">SARS-CoV-2 spillover</a> (Zenodo)<br /> •Polio cases linked to nOPV2 (<a title="" href= "https://www.science.org/content/article/first-polio-cases-linked-new-oral-vaccine-detected-africa">Science</a>; <a title="" href= "https://polioeradication.org/news-post/gpei-statement-on-cvdpv2-detections-in-burundi-and-democratic-republic-of-the-congo/"> GPEI statement</a>)<br /> •nOPV2 on <a title="" href= "https://www.microbe.tv/twiv/twiv-756/">TWiV 756</a><br /> •Engineering OPV to <a title="" href= "https://pubmed.ncbi.nlm.nih.gov/32330425/">prevent reversion</a> to neurovirulence (Cell Host Microbe)<br /> •<a title="" href= "https://www.nature.com/articles/s41541-022-00437-5">Stability of nOPV2</a> in chil