TWiV 936: Clinical update with Dr. Daniel Griffin

<p>In his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, effectiveness of COVID-19 vaccines over time prior to Omicron emergence in Ontario, Canada, nasal IgA wanes 9 months after hospitalization with COVID-19 and is not induced by subsequent vaccination,  resistance of SARS-CoV-2 Omicron subvariant BA.4.6 to antibody neutralization, persistent circulating SARS-CoV-2 spike associated with post-acute COVID-19 sequelae, and impact of COVID-19 vaccination on the risk of developing long-covid and on existing long-covid symptoms.</p> <p>Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode"><strong>Links for this episode</strong></h3> <ul> <li>Detection of poliovirus in <a href= "https://www.cdc.gov/mmwr/volumes/71/wr/mm7136a2.htm">immunosuppressed child</a> (CDC)</li> <li><a href= "https://emergency.cdc.gov/han/2022/han00474.asp">Severe respiratory illnesses</a> associated with rhinoviruses and/or enteroviruses (CDC)</li> <li>Effects of vaccination and previous <a href= "https://www.nejm.org/doi/full/10.1056/NEJMc2209371?query=featured_home">Omicron infection</a> in children (NEJM)</li> <li><a href= "https://j