TWiV 897: COVID-19 clinical update #113 with Dr. Daniel Griffin

<p>In COVID-19 clinical update #113, Dr. Griffin discusses tocilizumab use in hospitalized Patients, IL-6 inhibitors and mortality, Baricitinib in hospitalized patients, post-infection neurological sequelae, comparative effectiveness of Pfizer and Moderna vaccines, phase 2/3 study of Paxlovid, infection relapse following Paxlovid, pre-hospital administration of Remdesivir, and hospitalization with different variants.</p> <p>Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode"><strong>Links for this episode</strong></h3> <ul> <li><a href="https://pubmed.ncbi.nlm.nih.gov/35473844/">Timing of Tocilizumab</a> Use in Hospitalized Patients (NIH)</li> <li>Interleukin-6 inhibitors <a href= "https://www.ejinme.com/article/S0953-6205(22)00140-6/fulltext">reduce mortality</a> (European Journal of Internal Medicine) </li> <li><a href= "https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofac219/6575051"> Treatment Effect of Baricitinib</a> on Hospitalized Patients (IDSA)</li> <li>Post Infection <a href= "https://europepmc.org/article/PPR/PPR486308">Neurological Sequelae</a> (Res Square)</li> <li><a href= "https://www.nature.com/articles/s41467-022-30059-3">Comparative Effectiveness</a> of Pfizer and Moderna Vaccines (Nature Commun)</li> <li>Results from <a href= "https://www.pfizer.com/news/press-release/press-release-detail/pfizer-shares-top-line-results-phase-23-epic-pep-study">Phase 2/3 Study of Paxlovid</a> (Pfizer) </li> <li><a href= "https://assets.researchsquare.com/files/rs-1588371/v1/48342d2c-b3ea-4228-