TWiV 888: Molnupiravir with Richard Plemper

<p>Richard joins TWiV to discuss the SARS-CoV-2 antiviral drug Molnupiravir , including how it was discovered, its mechanism of action, whether it is a mutagen for cells, and the future of drugs for treatment of COVID-19.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello</a>, <a href="http://alandove.com/">Alan Dove</a>, and <a href="http://twitter.com/bioprofbarker">Brianne Barker</a></p> <p>Guest: <a href= "https://biomedical.gsu.edu/profile/plemper/">Richard Plemper</a></p> <p>Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode"><strong>Links for this episode</strong></h3> <ul> <li>Richard on <a href="https://www.microbe.tv/twiv/twiv-636/">TWiV 636</a></li> <li><a href= "https://pubmed.ncbi.nlm.nih.gov/33273742/">Molnupiravir</a> in ferrets (Nat Micro)</li> <li><a href="https://pubmed.ncbi.nlm.nih.gov/34741049/">Oral prodrug</a> of Remdesivir in ferrets (Nat Commun)</li> <li><a href="https://www.microbe.tv/twiv/twiv-888-letters/">Letters read</a> on TWiV 888</li> <li>Timestamps by <a href= "http://www.twitter.com/jrrmicro">Jolene</a>. Thanks!</li> </ul> <h3 id="weekly-picks-1-34-06">Weekly Picks</h3> <p><strong>Brianne</strong> – <a href= "https://biorender.com/poster-builder">BioRender Poster Builder</a><br /> <strong>Alan</strong> – <a href= "https://www.hexbug.com/pettoy">Hexbug</a> cat toys<br /> <strong>Vincent</strong> – <a href= "https://catalog.usmint.gov/american-innovation-2019-1-reverse-proof-coin-pennsylvania-19GF.html?cgid=null&q=polio&navid=search#q=pol