TWiV 716: COVID-19 clinical update #48 with Dr. Daniel Griffin

<p>In COVID-19 clinical update #48, Daniel Griffin reviews effect of spike amino acid changes on neutralization with monoclonal antibodies, Sputnik V safety and efficacy results, increased reactogenicity after a single vaccine dose in seropositive individuals, single dose vaccination in seropositive health care workers, and results of three clinical trials on the use of anticoagulants.</p> <p>Hosts: <a href="http://parasiteswithoutborders.com/">Daniel Griffin</a> and <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello</a></p> <p>Subscribe (free): <a href= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3><strong>Links for this episode</strong></h3> <ul> <li><a href= "https://www.biorxiv.org/content/10.1101/2021.01.25.428137v2">Resistance of variants</a> to mAb neutralization (bioRxiv)</li> <li>Safety and efficacy of <a href= "https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00234-8/fulltext"> Sputnik V</a> (Lancet)</li> <li>Increased vaccine <a href= "https://www.medrxiv.org/content/10.1101/2021.01.29.21250653v1">reactogenicity in seropositives</a> (medRxiv)</li> <li>Single dose vaccination in <a href= "https://www.medrxiv.org/content/10.1101/2021.01.30.21250843v2">seropositive health care workers</a> (medRxiv)</li> <li>Update on <a href= "https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html"> vaccine intervals</a> (CDC)</li> <li><a href= "https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3777268">Single dose</a> AZD1222 results (Lancet preprints)</li> <li>Three RCT on <a href= "https://www.nih.gov/news-events/news-releases/full-dose-blood-thinners-decreased-need-life-support-