Stroke Alert April 2022

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On Episode 15 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the April 2022 issue of Stroke: “<a href= "https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032953">Kawasaki Disease May Increase the Risk of Subsequent Cerebrovascular Disease</a>” and “<a href= "https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.034928">Effect of Moderate and Severe Persistent Hyperglycemia on Outcomes in Patients With Intracerebral Hemorrhage</a>.” She also interviews Dr. François Gros-Louis about his article “<a href= "https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032691">Moyamoya Disease Susceptibility Gene RNF213 Regulates Endothelial Barrier Function</a>.” Dr. Negar Asdaghi: 1) How would you counsel the parent of a child who has just recovered from Kawasaki disease on their child's future risk of having a stroke? 2) Should we or should we not treat stress hyperglycemia in the setting of acute intracerebral hemorrhage? 3) What is the CRISPR-Cas9 gene editing technology? And why, if you haven't heard of it already, you most definitely should be listening to this podcast? We're back here with the April issue of the Stroke Alert Podcast, and this is the latest in Stroke. Stay with us. Dr. Negar Asdaghi: Welcome back to another extremely informative Stroke Alert Podcast. My name is Negar Asdaghi. I'm an Associate Professor of Neurology at the University of Miami Miller School of Medicine, and your host for the monthly Stroke Alert Podcast. The April 2022 issue of Stroke contains a range of really exciting papers and topics. In the paper titled "<a href= "https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.038085">Vascular Response to Spreading Depolarization Predicts Stroke Outcome</a>," we have a really interesting in vivo mouse model of ischemic stroke, looking at the spreading patterns of cortical depolarization and the subsequen

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