Stroke Alert April 2021

<p>On Episode 3 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two featured articles from the April 2021 issue of <em>Stroke</em>. This episode also features a conversation with Dr. Simon Nagel, from Heidelberg University in Germany, to discuss his article “<a href= "https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030519">Predictors for Failure of Early Neurological Improvement After Successful Thrombectomy in the Anterior Circulation</a>.”</p> <p>Dr. Negar Asdaghi:                      </p> <p>1) Is Andexanet a cost-effective treatment for the reversal of coagulopathy in factor Xa-associated intracranial hemorrhage?</p> <p>2)  Are statins safe and efficacious in secondary prevention of stroke in the elderly population?</p> <p>3)  What are the predictors of futile recanalization amongst successfully treated patients with endovascular therapy?</p> <p>We have the answers to the above and much more in today's podcast. You're listening to Stroke Alert Podcast. Stay with us.</p> <p>Dr. Negar Asdaghi:                       From the Editorial Board of <em>Stroke</em>, welcome to the Stroke Alert Podcast. My name is Negar Asdaghi. I'm an Associate Professor of Neurology at the University of Miami Miller School of Medicine and your host for the monthly Stroke Alert Podcast. For the April 2021 issue of <em>Stroke</em>, we have an exciting program today where I have the privilege of interviewing Dr. Simon Nagel from Heidelberg University in Germany on predictors of failure of early neurological improvement or futile recanalization after successful thrombectomy. But first I want to review these two interesting articles.</p> <p>Dr. Negar Asdaghi:                       Factor Xa inhibitors, such as apixaban, edoxaban and rivaroxaban, are commonly used for prevention of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation. Bleeding is a serious adverse consequence of treatment with anticoagulants, including factor Xa inhibitors, with intracranial hemorrhage representing t