PubReading [258] - Visualization of macromolecular structures - S. O’Donoghue, A. Olson et al.

<p><strong>Structural biology</strong> is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. <strong>Visualization</strong> is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing <strong>three-dimensional structure</strong>s can provide insight and describe available methods and tools.</p><p><em>doi:10.1038/nmeth.1427 - 2010</em></p>