Podcast 847: ECMO CPR

<p><strong>Contributor: Aaron Lessen, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Extracorporeal Membrane Oxygenation (ECMO) has been attempted as an adjunct to CPR during cardiac arrest but few studies on outcomes exist </span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">One prior small study stopped early when it showed ECMO with CPR (ECPR) was significantly superior to CPR</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Recent large, multicenter randomized control study in Netherlands evaluated neurologic outcomes in CPR versus ECPR </span></li> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">At 30 days and 6 months no significant difference between the groups was found </span></li> </ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">More studies are required determine if certain patients may benefit from ECPR</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Belohlavek J, Smalcova J, Rob D, et al. Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.</span> <em><span style="font-weight: 400;">JAMA</span></em><span style= "font-weight: 400;">. 2022;327(8):737-747. doi:10.1001/jama.2022.1025</span></p> <p> </p> <p><span style="font-weight: 400;">Suverein MM, Delnoij TSR, Lorusso R, et al. Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest.</span> <em><span style= "font-weight: 400;">N Engl J Med</span></em><span style= "font-weight: 400;">. 2023;388(4):299-309. doi:10.1056/NEJMoa2204511</span></p> <p> </p> <p><em><span style="font-weight: 400;">Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD</spa