Podcast 762: Endocarditis

<p><strong>Contributor: Jared Scott, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Variability of organisms in infecting the myocardial valves</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Duke Criteria for Infective Endocarditis includes three categories that can be used to definitively diagnose endocarditis</span></li> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Pathologic Criteria</span></li> <ul> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">pathological evidence of infection</span></li> </ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Major Clinical Criteria</span></li> <ul> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">positive blood cultures</span></li> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">positive echocardiogram findings (TEE is more sensitive than a TTE)</span></li> </ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Minor Clinical Criteria (must include all of the below criteria)</span></li> <ul> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">Fever</span></li> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">Underlying heart condition or IV drug use</span></li> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">Vascular phenomena (includes Janeway’s lesions)</span></li> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">Immunologic phenomena (includes Osler’s nodes, Roth spots)</span></li> <li style="font-weight: 400;" aria-level="3"><span style= "font-weight: 400;">Positive blood cultures or serologic evidence of infection with bacteria known to cause endocarditis</span></li> </ul> </ul> <li style="font-weight: 400;" aria-level="1"><span style=