Podcast 744: Glucagon for Beta Blocker Toxicity

<p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Glucagon can be used to treat hypoglycemia and esophageal foreign body, but it can also be used in beta-blocker toxicity to bypass cardiac beta-blockade</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">The superior option for treating bradycardia due to beta-blocker toxicity is glucagon</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Glucagon has decreased efficacy in patients with heart failure, so increased doses up to 10 mg might be required in the event of beta-blocker toxicity</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Khalid MM, Galuska MA, Hamilton RJ. Beta-Blocker Toxicity. [Updated 2021 Jul 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from:</span> <a href= "https://www.ncbi.nlm.nih.gov/books/NBK448097/"><span style= "font-weight: 400;">https://www.ncbi.nlm.nih.gov/books/NBK448097/</span></a></p> <p><span style="font-weight: 400;">Rotella JA, Greene SL, Koutsogiannis Z, et al. Treatment for beta-blocker poisoning: a systematic review. Clin Toxicol (Phila). 2020;58(10):943-983. doi:10.1080/15563650.2020.1752918</span></p> <p><em><span style="font-weight: 400;">Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD</span></em></p> <p> </p> <p><span style="font-weight: 400;">The Emergency Medical Minute is excited to announce that we are now offering</span> <em><span style="font-weight: 400;">AMA PRA Category 1 credits™</span></em> <span style="font-weight: 400;">via online course modules. To access these and for more information, visit our website at</span> <a href= "https://emergencymedicalminute.org/cme-courses/"><span style= "font-weight: 400;">https://emergencymedicalminute.org/cme-courses/</span></a> <span style="font-weight: 400;">and create an account. </span></p> <p><a href= "https://www.