Podcast 700: Analgesics for Acute Musculoskeletal Pain

<p><strong>Contributor: Aaron Lessen, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Recent RCT compared pain relief in patients receiving five medications for acute musculoskeletal pain</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Acetaminophen 1000mg/ibuprofen 400 mg </span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Acetaminophen 1000mg/ibuprofen 800 mg</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Acetaminophen 300 mg/codeine 30 mg</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Acetaminophen 300mg/hydrocodone 5mg</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Acetaminophen 325mg/oxycodone 5mg</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">No significant difference in pain relief at 1 and 2 hours between all of 5 groups</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Bijur PE, Friedman BW, Irizarry E, Chang AK, Gallagher EJ. A Randomized Trial Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department. Ann Emerg Med. 2021;77(3):345-356. doi:10.1016/j.annemergmed.2020.10.004</span></p> <p> </p> <p><span style="font-weight: 400;">The Emergency Medical Minute is excited to announce that we are now offering</span> <em><span style="font-weight: 400;">AMA PRA Category 1 credits™</span></em> <span style="font-weight: 400;">via online course modules. To access these and for more information, visit our website at</span> <a href= "http://www.emergencymedicalminute.org/cme-courses"><span style= "font-weight: 400;">www.emergencymedicalminute.org/cme-courses/</span></a> <span style="font-weight: 400;">and