Podcast 667: Lactated Ringers for DKA

<p><strong>Contributor:  Aaron Lessen, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Recent study looked at whether lactated ringers might be a better choice for fluid resuscitation in patients with DKA compared to normal saline</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Normal saline can cause a hyperchloremic metabolic acidosis</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Time to resolution of acidosis was 4 hours less with lactated ringers compared to normal saline</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Time on an insulin drip decreased by about 4 hours with lactated ringers compared to normal saline</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">LR might be a better choice for fluid resuscitation in patients with DKA</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Self WH, Evans CS, Jenkins CA, et al. Clinical Effects of Balanced Crystalloids vs Saline in Adults With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials. JAMA Netw Open. 2020;3(11):e2024596. doi:10.1001/jamanetworkopen.2020.24596</span></p> <p><em><span style="font-weight: 400;">Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD</span></em></p> <p><br /> <br /></p>