Podcast 634: D10 for Hypoglycemia

<p><strong>Contributor: Dylan Luyten, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">D10 may be a better alternative to D50 in correcting hypoglycemia</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Risks of D50: </span></li> <li style="list-style: none; display: inline;"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Can cause extravasation injury</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Risk of rebound hypoglycemia</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">D10 does not have the same risks and has no significant difference in reversal time of hypoglycemia compared to D50</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-size: 10pt;"><span style= "font-weight: 400;">Kiefer MV, Gene Hern H, Alter HJ, Barger JB.</span> <a href= "https://pubmed.ncbi.nlm.nih.gov/24735872/"><span style= "font-weight: 400;">Dextrose 10% in the treatment of out-of-hospital hypoglycemia</span></a><span style= "font-weight: 400;">. Prehosp Disaster Med. 2014 Apr;29(2):190-4. doi: 10.1017/S1049023X14000284. Epub 2014 Apr 15. PMID: 24735872.</span></span></p> <p><span style="font-size: 10pt;"><span style= "font-weight: 400;">Moore C, Woollard M.</span> <a href= "https://pubmed.ncbi.nlm.nih.gov/15983093/"><span style= "font-weight: 400;">Dextrose 10% or 50% in the treatment of hypoglycaemia out of hospital? A randomised controlled trial</span></a><span style="font-weight: 400;">. Emerg Med J. 2005 Jul;22(7):512-5. doi: 10.1136/emj.2004.020693. PMID: 15983093; PMCID: PMC1726850.</span></span></p> <p><span style="font-size: 10pt;"><em><span style= "font-weight: 400;">Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD</span></em></span></p> <p><span style="font-size: 10pt;"><span style= "font-weight: 400;">The Emergency Medical M