Podcast 593: TXA for GIB

<p><strong>Contributor: Ricky Dhaliwal, MD, JD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;"><span style= "font-weight: 400;">Tranexamic acid (TXA) as shown to have mortality benefit to patients with traumatic GI hemorrhage but should it be used to achieve hemostasis in atraumatic GI bleeding?</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">HALT-IT study looked at TXA for the treatment of upper and lower GI hemorrhage and found no 5 day mortality benefit</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Patients given TXA also had higher occurrences of DVT and PE</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Roberts I, Coats T, Edwards P, et al.</span> <a href= "https://pubmed.ncbi.nlm.nih.gov/25409738/"><span style= "font-weight: 400;">HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial.</span></a> <em><span style= "font-weight: 400;">Trials</span></em><span style= "font-weight: 400;">. 2014;15:450. Published 2014 Nov 19. doi:10.1186/1745-6215-15-450</span></p> <p> </p> <p><em><span style="font-weight: 400;">Summarized by Jackson Roos, MS4 | Edited by Erik Verzemnieks, MD</span></em></p> <p><br /> <br /></p> <div id="highlighter--hover-tools" style="display: none;"> <div id="highlighter--hover-tools--container"> <div class="highlighter--icon highlighter--icon-copy" title="Copy">  </div> <div class="highlighter--separator"> </div> <div class="highlighter--icon highlighter--icon-delete" title= "Delete"> </div> </div> </div>