October 2020 Discover CircRes

<p>This month on Episode 17 of the Discover CircRes podcast, host Cindy St. Hilaire highlights four featured articles from the September 25 and October 9 issues of Circulation Research. This episode features an in-depth conversation with Drs David Dichek, Sina Gharib and Tomáš Vaisar regarding their study titled <a href= "https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.317295">Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture.</a></p> <p><br /> Article highlights:<br /> Cai, et al. <a href= "https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.119.316470?af=R"> Single Cell RNA-Seq in Arteriosclerosis</a><br /> Schuhmann, et al. <a href= "https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.316655">CD84 in Ischemic Stroke</a><br /> VanOudenhove, et al. <a href= "https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.316704">Gene Regulatory Dynamics of Developing Human Heart</a><br /> Nie, et al. <a href= "https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.316943">Periostin is a Target to Treat PH</a></p> <p><br /> Dr Cindy St. Hilaire: Hi, welcome to Discover CircRes, the podcast of the American Heart Association's journal Circulation Research. I'm your host, Dr Cindy St. Hilaire, from the Vascular Medicine Institute at the University of Pittsburgh, and today I'll be highlighting four articles selected from the late September and early October issues of CircRes. I'll also be interviewing Drs David Dichek, Sina Gharib, and Tomáš Vaisar regarding their study titled Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture.<br /> The first article I want to share is titled Single Cell RNA Sequencing of Allograft Cells in Transplant Arteriosclerosis. The first author is Jingjing Cai and the corresponding author is Qingbo Xu from Zhejiang university in Hangzhou, China. Arteriosclerosis is a major contributor to organ transplant failure. The thickening and stiffening of arteries within the grafts results in diminished blood flow supplies and diminished or