Mitochondrial Disease and the Immune System

<h5>Talking points include:</h5> <ul class="list"> <li>What is the immune system and why is it important?</li> <li>Infection and mitochondrial disease</li> <li>Immune function in mitochondrial disease</li> </ul> <h5>About The Speaker:</h5> <p><em><strong>Dr. Peter McGuire</strong></em></p> <p style="font-style: inherit; font-weight: inherit;"><span style="font-style: inherit; font-weight: inherit;">Dr. Peter McGuire received his MBBCh (with Honours) from the Royal College of Surgeons in Ireland in 2003. Following a combined residency in Pediatrics and Medical Genetics at Mount Sinai Medical Center in New York City, he remained as an Assistant Professor in the Program for Inherited Metabolic Diseases at Mount Sinai. Dr. McGuire is board certified in Pediatrics, Clinical Genetics and Biochemical Genetics. </span></p> <p style="font-style: inherit; font-weight: inherit;"><span style="font-style: inherit; font-weight: inherit;">In 2010, Dr. McGuire moved to the National Human Genome Research Institute (NHGRI) at the National Institutes of Health to join the Physician Scientist Development Program. He was appointed to the position of tenure track Investigator in 2016. </span></p> <p style="font-style: inherit; font-weight: inherit;"><span style="font-style: inherit; font-weight: inherit;">Throughout his career, Dr. McGuire has been focused on improving the care of patients with disorders of mitochondrial metabolism. By combining his training in Immunology and Biochemical Genetics, he has fashioned a translational research program to understand the interplay between mitochondrial metabolism and the immune system. As Head of the Metabolism, Infection and Immunity Section (MINIS) at NHGRI, Dr. McGuire and his team study the interplay between metabolism and the immune system in patients with inborn errors of mitochondrial metabolism. The group focuses on two aspects of immunometabolism:</span></p> <p style="font-style: inherit; font-weight: inherit;"><strong><strong style="font-style: inherit;"