Immune 36: Aberrant immunity in COVID-19

<div class="entry-content"> <p>Immune describes the striking loss of germinal centers in lymph nodes and spleen in patients with severe COVID-19, providing an explanation for short-lived humoral immunity and limited somatic hypermutation of antibodies to SARS-CoV-2.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello" target="_blank" rel="noreferrer noopener">Vincent Racaniello</a>, <a href= "http://www.twitter.com/stephanielangel">Stephanie Langel</a>, <a href="http://www.twitter.com/cindyleifer" target="_blank" rel= "noreferrer noopener">Cynthia Leifer</a>, and <a href= "http://www.twitter.com/BioProfBarker">Brianne Barker</a></p> <p>Guest: <a href= "https://medicine.iu.edu/faculty/15118/dent-alexander">Alexander Dent</a></p> <p>Subscribe (free): <a href= "https://itunes.apple.com/us/podcast/immune/id1305309644" target= "_blank" rel="noreferrer noopener">iTunes</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL2ltbXVuZS5saWJzeW4uY29tL3Jzcw%3D%3D" target="_blank" rel="noreferrer noopener">Google Podcasts</a>. <a href="http://immune.libsyn.com/rss" target= "_blank" rel="noreferrer noopener">RSS</a>, <a href= "http://eepurl.com/Gcw59" target="_blank" rel= "noreferrer noopener">email</a><br /> Become a <a href="https://www.microbe.tv/contribute" target= "_blank" rel= "noreferrer noopener">patron</a> of Immune!</p> <h3>Links for this episode</h3> <ul> <li><a href= "https://www.cell.com/cell/pdf/S0092-8674(20)31067-9.pdf">Loss of germinal centers</a> in severe COVID-19 patients (Cell)</li> <li>Time stamps by <a href="http://www.twitter.com/jrrmicro" target="_blank" rel="noreferrer noopener">Jolene</a>. Thanks!</li> </ul> <p>Music by Steve Neal.<br /> Immune logo image by <a href= "https://en.wikiversity.org/wiki/File:Blausen_0077_Basophil.png" target="_blank" rel="noreferrer noopener">Blausen Medical</a><br /> <br /> Send your immunology questions and comments to immune@microbe.tv</p> </div> <p> </p>