Episode 38: Acute Hyperglycemic Episodes

<p>Dr. Nadine Palermo, an endocrinologist and the Associate Director of the Acute&nbsp;Diabetes Care program at Brigham and Women’s Hospital, talks with Joyce Zhou (host) and Jakub Glowala (case presenter) to discuss acute hyperglycemic episodes. The discussion begins with a case of a patient presenting with dehydration, altered&nbsp;mental status, emesis, and suspected symptomatic hyperglycemia. Dr. Palermo then brings us up to speed on the pathophysiology behind diabetic ketoacidosis (DKA) and&nbsp;hyperosmolar hyperglycemic state (HHS), underscoring the role of osmotic diuresis and counter-regulatory hormones in exacerbating the two conditions. Dr. Palermo instructs us on the “classic” signs of a patient presenting with DKA, while cautioning us against relying solely on these textbook findings, as the workup often involves a holistic combination of BMP, urinalysis, ABG/VBGs, and history-taking. The episode closes with a discussion of DKA and HHS treatment, in addition to some clinical pearls.</p> <p><a href="https://www.runthelistpodcast.com/endocrinology/#acute-hyperglycemia">https://www.runthelistpodcast.com/endocrinology/#acute-hyperglycemia</a></p>