COVID-19 Digest: Neurological Manifestations of COVID-19

<p><span style="font-weight: 400;">Accumulating clinical evidence suggests that many patients with COVID have neurological symptoms a</span><span style="font-weight: 400;">nd that some may even present with neurologic manifestations of the disease. Most COVID patients have a cough, respiratory distress, and</span> <span style="font-weight: 400;">while clinicians often speak about how similar the presentations of patients with respiratory COVID are, it’s worth looking at the possibility that COVID has atypical presentations, too.</span><span style="font-weight: 400;">There’s very good evidence that coronaviruses can infect all sorts of human cells--not just those in the respiratory tract. A few weeks ago we discussed ACE inhibitors and NSAIDs and SARS COV2 and you may remember that the virus attaches to the ACE2 receptor--a receptor which is found on a wide range of human cells. What are the chances the virus can infect a patients brain cells, cranial nerves, peripheral nerves?</span></p> <p><strong>Host</strong>: Elizabeth Esty, MD</p> <p><strong>Research</strong> <strong>By</strong>: Tanisha Crosby-Attipoe & Mason Tuttle</p> <p><strong>Sound</strong> <strong>Editing</strong> <strong>By</strong>: Stephen Bahmani</p> <p><strong>Time</strong> <strong>Stamps</strong>:</p> <p>0:23 - Numbers</p> <p>1:25 - Possible Neurological Manifestations of COVID</p> <p>4:15 - <span style="font-weight: 400;">What are the chances the virus can infect a patients brain cells, cranial nerves, peripheral nerves?</span></p> <p><span style="font-weight: 400;">4:55 - The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients</span></p> <p>8:24 - early neurological research from NEJM in February</p> <p>9:10 - some early research indicated possible neurological manifestations</p> <p>10:05 - COVID and serious CV incidents</p> <p>10:40 - Italian Neurologists urge other nations to be alert for neuro presentations of COVID</p> <p>11:11 - Case report in <em>Radiology</em>, COVID patient with encephal