Are You Out Of Energy?

<p><span style="font-weight: 400;">In today’s episode, Dr. Gladden will be joined by the world’s leading nutritional biochemist, expert on health optimization, and ingredientologist, Shawn Wells, MPH, LDN, RD, CISSN, FISSN. </span></p> <p> </p> <p><span style="font-weight: 400;">The two discuss energy and fatigue related to mitochondrial dysfunction, resilience, depression, and protein BDMF. We also talk about metabolic flexibility and the Ketogenic Diet. We end with Shawn’s three secrets for longevity. </span></p> <p> </p> <p><span style="font-weight: 400;">Dr. Gladden presents today´s guest Shawn Wells, a nutritional biochemistry expert in health optimization and discusses the health issues he has been fighting and his book “The Energy Formula” (1:16);</span></p> <p><span style="font-weight: 400;">Dr. Gladden starts the conversation by introducing energy and the aging process as a topic (3:35);</span></p> <p><span style="font-weight: 400;">Shawn Wells speaks about ICES and mitochondrial dysfunction (metabolic disfunction) (4:40);</span></p> <p><span style="font-weight: 400;">The reason for fatigue: metabolic predisposition (no back to normal function) and chronic infection that damage the mitochondria from the outside (6:37);</span></p> <p><span style="font-weight: 400;">Dr. Gladden introduces metabolic flexibility to connect the ideas about Keto Diet (11:33);</span></p> <p><span style="font-weight: 400;">Dr. Gladden discusses a study about metformin and its potential impact on longevity, and mentions how metformin activates AMPK and lowers insulin resistance by increasing insulin receptors (13:27);</span></p> <p><span style="font-weight: 400;">Shawn Wells talks about the differences and benefits from metformin (14:14);</span></p> <p><span style="font-weight: 400;">Dr. Gladden continues discussing metformin with Shawn Wells, who mentions B-12 depletion with metformin (16:35);</span></p> <p><span style="font-weight: 400;">Dr. Gladden reintroduces fatigue into the discussion (16:54);</span></p> <p><span style="fo