330 - Vascular Changes in Alzheimer's Disease: January 2023

<p>Elyn's back with more insight from the field on how blood vessel health impacts brain health. Tune in for a journey through mechanisms underlying increased risk from "vascular risk factors" like hypertension, diabetes, and atrial fibrillation, lots of neuroimaging studies providing clinical insights, and several interesting novel therapeutic avenues. If you weren't already convinced that the vasculature is relevant in the context of AD, you sure will be after this episode!  </p><p>Sections in this episode:  </p><p>Cerebral blood flow and hypoperfusion (4:08)  </p><p>More clinical insights (10:53)  </p><p>Blood-brain barrier and amyloid-endothelial cell interactions (19:52)  </p><p>Therapeutic avenues targeting the vasculature (27:12) </p><p>-------------------------------------------------------------- </p><p>To find the numbered bibliography with all the papers covered in this episode, click <a href="https://drive.google.com/file/d/1jxLnkb02ovKVtHq_MNwg738QyyYWmA4y/view">here</a>, or use the link below:</p><p>https://drive.google.com/file/d/1jxLnkb02ovKVtHq_MNwg738QyyYWmA4y/view</p><p>To access the folder with ALL our bibliographies, follow <a href="https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharing">this link</a> (it will be updated as we publish episodes and process bibliographies), or use the link below:</p><p><a href="https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharing">https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharing</a></p><p>You can also find all of our bibliographies on our website: <a href="http://www.amindr.com">amindr.com</a>. </p><p>-------------------------------------------------------------- </p><p>We at AMiNDR are eager to hear from you! We opened up a survey available until the end of April for you to tell us what we are doing well, and where we can improve. Access the survey at <a href="http://tinyurl.com/amindrsurvey">tinyurl.com/amindrsurvey</a>. All survey responses will be anonymous. By