295: Uncultured and Unmutable

<p dir="ltr">TWiM explains how phages avoid tRNA-targeting host defenses, and discovery of a new antibiotic from an uncultured bacterium that binds to an immutable target.</p> <p>Hosts: <a href="https://twitter.com/profvrr" target="_blank" rel="noopener">Vincent Racaniello</a>, <a href= "http://academicdepartments.musc.edu/immunology/Faculty/schmidt.html" target="_blank" rel="noopener">Michael Schmidt</a>, and <a href= "https://biology.wustl.edu/people/petra-levin" target="_blank" rel= "noopener">Petra Levin</a>,</p> <p>Become a <a href="http://www.microbe.tv/contribute" target= "_blank" rel="noopener">patron</a> of TWiM.</p> <h2><strong>Links for this episode</strong></h2> <ul> <li><a href="https://elifesciences.org/articles/85183" target= "_blank" rel="noopener">Phages avoid tRNA-targeting</a> host defenses (eLife)</li> <li><a href="https://seaphages.org/" target="_blank" rel= "noopener">Sea phages</a></li> <li><a href="https://phagesdb.org/people/" target="_blank" rel= "noopener">Actinobacteriophage database</a></li> <li>New antibiotic from <a href= "https://www.biorxiv.org/content/10.1101/2023.05.15.540765v1">uncultured bacterium</a> (bioRxiv)</li> <li><a href= "https://foreignpolicy.com/2015/09/30/the-age-of-infection-antibiotics-microbes-germ-ichip/" target="_blank" rel="noopener">The age of infection</a> (For Policy)</li> <li><a href="https://pubmed.ncbi.nlm.nih.gov/35922513/" target= "_blank" rel="noopener">Killing bacteria by teixobactin</a> (Nature)</li> <li><a href="https://asm.org/twimpoll" target="_blank" rel= "noopener">Take the TWiM Listener surve</a><a href= "https://asm.org/twimpoll" target="_blank" rel= "noopener">y!</a></li> </ul> <p>Send your microbiology questions and comments (email or recorded audio) to <a href= "mailto:twim@microbe.tv">twim@microbe.tv</a></p>