289: Viral Defense and Counter-Defense

<p dir="ltr">TWiM highlights viral defense and counter-defense: cGAS mediated ubiquitination to counter infection, and viral sponges that sequester nucleotide signals to inactivate immunity.</p> <p>Hosts: <a href="https://twitter.com/profvrr" target="_blank" rel="noopener">Vincent Racaniello</a>, <a href= "http://academicdepartments.musc.edu/immunology/Faculty/schmidt.html" target="_blank" rel="noopener">Michael Schmidt</a>, <a href= "https://twitter.com/umichmichele" target="_blank" rel= "noopener">Michele Swanson</a>, <a href= "https://biology.wustl.edu/people/petra-levin" target="_blank" rel= "noopener">Petra Levin</a>.</p> <p>Become a <a href="http://www.microbe.tv/contribute" target= "_blank" rel="noopener">patron</a> of TWiM.</p> <h2><strong>Links for this episode</strong></h2> <ul> <li><a href="https://www.nature.com/articles/s41586-023-05862-7" target="_blank" rel="noopener">Ubiquitin-like conjugation by bacterial cGAS</a> (Nature)</li> <li>Jumpin’ Jack Flash (<a href= "https://www.microbe.tv/twiv/twiv-222-jumpin-jack-flash-its-a-gas-gas-gas/" target="_blank" rel="noopener">TWiV 222</a>)</li> <li><a href= "https://www.sciencedirect.com/science/article/pii/S0966842X23001166" target="_blank" rel="noopener">Viral sponges inactivate anti-phage immunity</a> (Trends Micro)</li> <li><a href= "https://www.sciencedirect.com/science/article/pii/S0959440X19300478" target="_blank" rel="noopener">cGAS and CD-NTase enzymes</a> (Curr Opin Struct Biol)</li> <li><a href="https://asm.org/twimpoll" target="_blank" rel= "noopener">Take the TWiM Listener surve</a><a href= "https://asm.org/twimpoll" target="_blank" rel= "noopener">y!</a></li> </ul> <p>Music used on TWiM is by <a href= "http://ronaldjenkees.com/">Ronald Jenkees</a></p> <p>Send your microbiology questions and comments (email or recorded audio) to <a href="mailto:twim@microbe.tv">twim@microbe.tv</a></p>