
225: Lag phase is no slouch
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Description
<p><span style="font-weight: 400;">The TWiM team explores how delivery of an enzyme into competitor cells leads to synthesis of (p)ppApp, depletion of ATP, deregulation of metabolic pathways, and cell death, and a refinement of our typical view of bacterial lag phase as a period of nonreplication.</span></p> <p><span style="font-weight: 400;">Hosts: <a href= "http://www.virology.ws/">Vincent Racaniello</a>, <a href= "http://schaechter.asmblog.org/schaechter/">Elio Schaechter</a>, and <a href= "http://academicdepartments.musc.edu/immunology/Faculty/schmidt.html"> Michael Schmidt</a></span></p> <p><span style="font-weight: 400;">Become a</span> <a href= "http://www.microbe.tv/contribute"><span style= "font-weight: 400;">patron</span></a> <span style= "font-weight: 400;">of TWiM.</span></p> <p><span style="font-weight: 400;">Links for this episode:</span></p> <ul> <li style="font-weight: 400;"><span style= "font-weight: 400;">Killing competitors by</span> <a href= "https://www.nature.com/articles/s41586-019-1735-9"><span style= "font-weight: 400;">synthesis of (p)ppApp</span></a> <span style= "font-weight: 400;">(Nature)</span></li> <li style="font-weight: 400;"><a href= "https://jb.asm.org/content/201/7/e00697-18"><span style= "font-weight: 400;">Lag phase</span></a> <span style= "font-weight: 400;">is a dynamic period (J Bact)</span></li> <li style="font-weight: 400;"><a href= "https://jb.asm.org/content/201/7/e00697-18"><span style= "font-weight: 400;">Image credit</span></a></li> </ul> <p><span style="font-weight: 400;">Music used on TWiM is composed and performed by <a href="http://ronaldjenkees.com/">Ronald Jenkees</a> and used with permission.</span></p> <p><span style="font-weight: 400;">Send your microbiology questions and comments to twim@microbe.tv</span></p>