212: A coronavirus outbreak and IRF4 deficiency in Whipple’s disease

<p><span style="font-weight: 400;">The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple’s disease. </span></p> <ul> <li style="font-weight: 400;"><span style= "font-weight: 400;">2019-nCoV</span> <a href= "https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6"> <span style="font-weight: 400;">case tracking</span></a> <span style="font-weight: 400;">(JHU)</span></li> <li style="font-weight: 400;"><a href= "https://www.ncbi.nlm.nih.gov/pubmed/31986264"><span style= "font-weight: 400;">Clinical features</span></a> <span style= "font-weight: 400;">of infection with 2019-nCoV (Lancet)</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Early</span> <a href= "https://www.nejm.org/doi/full/10.1056/NEJMoa2001316?query=featured_coronavirus"> <span style="font-weight: 400;">transmission dynamics</span></a> <span style="font-weight: 400;">of 2019-nCoV (NEJM)</span></li> <li style="font-weight: 400;"><a href= "https://www.nejm.org/doi/full/10.1056/NEJMoa2001017?query=featured_coronavirus"> <span style="font-weight: 400;">Isolation</span></a> <span style= "font-weight: 400;">of 2019-nCoV (NEJM)</span></li> <li style="font-weight: 400;">TLR4 defect in <a href= "https://www.ncbi.nlm.nih.gov/pubmed/29537367">Whipple’s disease</a> (eLife)</li> </ul> <p>Become a <a href="http://www.patreon.com/microbetv" target= "_blank" rel="noreferrer noopener">Patron of TWiM</a>!</p> <p>Music used on TWiM is composed and performed by <a href= "http://ronaldjenkees.com/" target="_blank" rel= "noreferrer noopener">Ronald Jenkees</a> and used with permission.</p> <p>Send your microbiology questions and comments to <a target="_blank" rel= "noreferrer noopener">twim@microbe.tv</a></p>