189: RNA-Based Vaccination for Grapevine Viruses

<p class="MsoNormal"><span style= "mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;">RNA Interference, known as RNAi, is a</span> <span class= "hgkelc"><span lang="EN" style="mso-ansi-language: EN;" xml:lang= "EN">biological process that</span></span> leads to the silencing of gene expression. <span class="hgkelc"><span style= "mso-ansi-language: EN;"><span style= "mso-spacerun: yes;"> </span></span></span><span style= "mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;">A lot of plant viruses are RNA viruses including grapevine leafroll-associated virus and grapevine red blotch virus.</span> <span style= "mso-bidi-font-size: 10.0pt; line-height: 110%; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;">  Yen-Wen Kuo,</span> Assistant Professor <span style= "mso-bidi-font-size: 10.0pt; line-height: 110%; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;">in the Department of Plant Pathology at the University of California, Davis is researching ways to i</span><span style= "mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;">nduce RNAi in grapevines to target virus. Growers may have heard of double-stranded RNA sprays which are intended to initiate RNAi. The challenge has been that double-stranded RNA breaks down quickly in the elements. The Kou lab is working to improve this process and look for alternatives that will have little impact on the ecology.</span></p> <h2><span style= "mso-fareast-font-family: 'Times New Roman';">Resources:</span></h2> <ul> <li class="MsoNormal"><a href= "https://www.vineyardteam.org/resources/resource-library/pest-management.php?id=793"> 71: New Techniques to Detect Grapevine Leafroll Disease</a></li> <li class="MsoNormal"><a href= "https://www.vineyardteam.org/resources/resource-library/pest-management.php?id=927"> 131: Virus Detection in Grapevines</a></li> <li class="MsoNormal"><a href= "https://pubmed.ncbi.nlm.nih.gov/35713600/"><span style= "mso-bidi-font-size: 10.0pt; line-height: 110%; mso-ascii-font-fami